As we saw, we have a number of ways to create links and URL representations, but when it comes to creating a link, which method should we use? There are advantages and disadvantages for each one.
When it comes to URL, as mentioned, it's a good idea to stick to hardcoding routes rather than URIs. However, if you are working with dynamic data, such as user input or stored strings, the other methods are perfectly valid. I recommend that you look at the Url class in detail because you will be using it quite a bit as you develop Drupal 8 modules.
Regarding the actual links, using the service to generate a link means that you are creating a string at your point in the code. This means that it cannot be altered later in the process. On the other hand, using the Link class falls nicely in line with the entire render array rationale of delaying the actual generation to the last possible moment. We will talk more about render arrays later on. So, the choice you make depends on the link you need to generate and your answer to the following question: is the link something that might have to be alterable by other modules/themes? If so, proceed with the render array. Otherwise, you might consider generating if you can inject the service properly.