- 中國臨床腫瘤學會(CSCO)惡性血液病診療指南·2020
- 中國臨床腫瘤學會指南工作委員會
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- 2020-08-26 18:35:11
1.3 預后
預后分組參考G?kbuget等 [5]發表的危險度分組標準(表1-1)。細胞遺傳學分組參考NCCN 2019(表1-2)。
ALL診斷確立后,應根據具體分型、預后分組采用規范化的分層治療策略,以取得最佳治療效果。
表1-1 成人ALL預后分組

表1-1 成人ALL預后分組(續表)

注:CR.完全緩解;MRD.微小殘留病;?.可能有意義,但尚未達成共識
表1-2 NCCN2019年B-ALL細胞遺傳學危險度分組

參考文獻
[1] DE HAAS V, ISMAILA N, ADVANI A, et al. Initial Diagnostic Work-Up of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement of the College of American Pathologists and American Society of Hematology Guideline. J Clin Oncol, 2019 Jan 20, 37 (3): 239-253.
[2] NCCN Clinical Practice Guidelines in Oncology-Acute Lymphoblastic Leukemia (2019 Version 2) [DB/OL]. http: //www. nccn. org.
[3] BENE MC, CASTOLDI G, KNAPP W, et al. Proposals for the immunological classi fi cation of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia, 1995, 9 (10): 1783-1786.
[4] ARBER DA, ORAZI A, HASSERJIAN R, et al. The 2016 revision to the World Health Organization classi fi cation of myeloid neoplasms and acute leukemia. Blood, 2016, 127: 2391-2405.
[5] G?KBUGET N, HOELZER D. Treatment of adult acute lymphoblastic leukemia. Semin Hematol, 2009, 46 (1): 64-75.